Article

This systematic review with a meta-analysis of studies was carried out to
evaluate the potential of overwork weakness on the basis of grip strength of
dominant and nondominant hands in individuals with Charcot-Marie-Tooth disease
(CMT). Numerous electronic databases were searched from the earliest records to
February 2016. Studies of any design including participants older than 18 years
of age with a confirmed diagnosis of CMT that measured grip strength of both
hands using dynamometric testing were eligible for inclusion. Of 12 593 articles
identified following removal of duplicates, five articles fulfilled the criteria.
A total of 166 participants, mostly with CMT1 or CMT2, were described from the
studies included. Hand and finger pinch grip strength for the dominant compared
with the nondominant hand was not statistically different.
There is no definitive
evidence that preferential use of the dominant hand in CMT impairs function
relative to the nondominant hand. Thus, robust exercise trials of progressive
resistance training are needed to understand the extent of adaptations possible
and provide evidence of the safety of such regimens.

Langue : ANGLAIS