Article

Vitamin D deficiency is a frequent pathology associated with
cardiovascular diseases and physical performance. OBJECTIVE: To study the link
between 25-hydroxyvitamin D (25OHD) level and physical performance and gain in
physical performance after cardiovascular rehabilitation (CVR) with vitamin D
deficiency. METHODS: 25OHD level was assessed in a retrospective cohort of
patients admitted for CVR. Data were collected on physical fitness [6-min walk
test distance (6MWD) in percentage of predicted, maximal power (Pmax)]. The
threshold of vitamin D deficiency was 20ng/ml chosen according to the literature.
RESULTS: Among the 131 patients included, as compared with those with
nondeficiency (n=83; 63%), patients with vitamin D deficiency (n=48, 37%) had
lower initial 6MWD (82+/-18 vs 89+/-12% predicted, P=0.009) and Pmax (100+/-58 vs
120+/-39W, P=0.006). After CVR, this difference was maintained. The improvement
in 6MWD and Pmax was significantly lower with deficiency than nondeficiency, for
an increase of 11+/-8% versus 14+/-9% predicted (P=0.048) and 10+/-30 versus
32+/-30W (P=0.00001), respectively. CONCLUSION: Vitamin D deficiency may be
associated with impaired physical fitness before CVR and a smaller gain in
physical fitness with CVR, probably related to the action of vitamin D on the muscle.
CI - Copyright (c) 2016. Published by Elsevier Masson SAS.

Langue : ANGLAIS