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An RCT to Treat Learning Impairment in Traumatic Brain Injury : The TBI-MEM Trial

CHIARAVALLOTI ND; SANDRY J; MOORE NB; DELUCA J
NEUROREHABIL NEURAL REPAIR , 2016, vol. 30, n° 6, p. 539-550
Doc n°: 181353
Localisation : Documentation IRR

D.O.I. : http://dx.doi.org/DOI:10.1177/1545968315604395
Descripteurs : AF3 - TRAUMATISME CRANIEN, AD671 TROUBLES DE LA MEMOIRE

OBJECTIVE: To examine the efficacy of the modified Story Memory Technique (mSMT)
to improve learning (ie, acquisition) and memory in participants with TBI.
The mSMT is a behavioral intervention that teaches context and imagery to facilitate
learning within 10 sessions over 5 weeks. METHODS:
A total of 69 participants
with moderate-severe Traumatic Brain Injury (TBI), 35 in the treatment group and
34 in the placebo control group, completed this double-blind, placebo-controlled
randomized clinical trial.
A baseline neuropsychological assessment was
administered, including questionnaires assessing everyday memory. Repeat
assessments were conducted immediately posttreatment and 6 months following
treatment. Participants in the treatment group were randomly assigned to a
booster session or a non-booster session group after completion of treatment with
the mSMT to examine the efficacy of monthly booster sessions in facilitating the
treatment effect over time. RESULTS: The treatment group demonstrated significant
improvement on a prose memory task relative to the placebo group posttreatment
(eta(2) = 0.064 medium effect). Similar results were noted on objective measures
of everyday memory, specifically prospective memory (Cohen's w = 0.43, medium
effect), and family report of disinhibition in daily life
(eta(2) = 0.046, medium
effect). CONCLUSION: The mSMT is effective for improving learning and memory in
TBI. CLASSIFICATION OF EVIDENCE: Based on widely accepted classification systems
for treatment study design, this study provides class I evidence that the mSMT
behavioral intervention improves both objective memory and everyday memory in
persons with TBI over 5 weeks. Thus, this study extends the evidence for efficacy
of the treatment protocol to a sample of persons with TBI.
CI - (c) The Author(s) 2015.

Langue : ANGLAIS

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