Article

Chronic traumatic encephalopathy (CTE) is a neuropathologic diagnosis typically
made in human brains with a history of repetitive traumatic brain injury (rTBI).
It remains unknown whether CTE occurs exclusively after rTBI,
or whether a single
TBI (sTBI) can cause CTE. Similarly, it is unclear whether impact (eg, motor
vehicle accidents) and non-impact (eg, blasts) types of energy transfer trigger
divergent or common pathologies. While it is established that a history of rTBI
increases the risk of multiple neurodegenerative diseases (eg, dementia,
parkinsonism, and CTE), the possible pathophysiologic and molecular mechanisms
underlying these risks have yet to be elucidated.
CI - Published by Elsevier Inc.

Langue : ANGLAIS