Article

Hylan G-F 20 (Synvisc-One) is a hyaluronic acid derivative used for
viscosupplementation of synovial fluid in osteoarthritic joints. Injection of
hylan G-F 20 is Federal Drug Administration approved for use in knee
osteoarthritis and is generally well tolerated with few reported adverse effects,
the most common being local pain or swelling.
We present the case of a
72-year-old man with bilateral, diffuse, joint pain and swelling with elevated
inflammatory markers suggestive of a systemic inflammatory polyarthropathy that
developed acutely 2 days after lumbar zygapophyseal joint injection with hylan
G-F 20. Systemic effects after hylan G-F 20 injection have not been well
documented, and this is the first reported case of systemic inflammatory
polyarthritis after injection, to our knowledge. Further research is needed to
better establish the safety and efficacy of lumbar zygapophyseal joint injections
with hylan G-F 20.

Langue : ANGLAIS