Article

OBJECTIVE: To examine clinical outcomes and completion rates of cardiac
rehabilitation in women with breast cancer and treatment-related heart failure.
METHODS: Data for women with breast cancer and treatment-related heart failure
were compared with those for age-matched women with coronary artery disease.
Retrospective data were obtained from the Toronto Rehabilitation Institute
database for dates between 1998 and 2011, for cardiopulmonary exercise test
results at baseline and 6 months, body composition measures, and cardiac
rehabilitation completion rates. RESULTS: A total of 29 women with breast cancer
and treatment-related heart failure (mean 57 years (standard deviation (SD) 9.4))
and 29 age-matched women with coronary artery disease were identified. There was
no significant difference between the proportion of women with breast cancer and
treatment-related heart failure and those with coronary artery disease who
completed the programme.
Peak aerobic power (VO2peak) increased in the breast
cancer and treatment-related heart failure group (mean 16.2 ml-1.kg-1.min-1 (SD
3.4) to mean 18.5 ml-1.kg-1.min-1 (SD 4.5) ; p = 0.002) and in the coronary
artery disease group (mean 18.9 ml-1.kg-1.min-1 (SD 4.5) to mean 20.8
ml-1.kg-1.min-1 (SD 4.9); p = 0.01). Body fat percentage increased in the breast
cancer and treatment-related heart failure group (mean 34.8% (SD 8.5) to mean
36.3% (SD 6.9); p = 0.04). CONCLUSION : Women with breast cancer and
treatment-related heart failure participating in cardiac rehabilitation
demonstrate similar significant gains in VO2peak and similar completion rates to
those of age-matched women with coronary artery disease. Further research is
needed to determine interventions that improve body composition in women with
breast cancer and treatment-related heart failure.

Langue : ANGLAIS