Article

Finding, testing and demonstrating efficacy of new treatments for stroke recovery
is a multifaceted challenge. We believe that to advance the field,
neurorehabilitation trials need a conceptually rigorous starting framework. An
essential first step is to agree on definitions of sensorimotor recovery and on
measures consistent with these definitions. Such standardization would allow
pooling of participant data across studies and institutions aiding meta-analyses
of completed trials, more detailed exploration of recovery profiles of our
patients and the generation of new hypotheses. Here, we present the results of a
consensus meeting about measurement standards and patient characteristics that we
suggest should be collected in all future stroke recovery trials. Recommendations
are made considering time post stroke and are aligned with the international
classification of functioning and disability. A strong case is made for addition
of kinematic and kinetic movement quantification. Further work is being
undertaken by our group to form consensus on clinical predictors and pre-stroke
clinical data that should be collected, as well as recommendations for additional
outcome measurement tools. To improve stroke recovery trials, we urge the
research community to consider adopting our recommendations in their trial
design.

Langue : ANGLAIS