Article

AIM: To study the prevalence of congenital anomalies among children with cerebral
palsy (CP) born at term or late preterm, and if CP subtypes and clinical
manifestations differ between children with and without congenital anomalies.
METHOD: This was a cross-sectional study using data from the Cerebral Palsy
Register of Norway and the Medical Birth Registry of Norway. All children with
congenital CP born at and later than 34 weeks' gestation in Norway from 1999 to
2009 were included. Anomalies were classified according to the European
Surveillance of Congenital Anomalies classification guidelines. Groups were
compared using Fisher's exact test, Kruskal-Wallis test, and the Mann-Whitney U
test. RESULTS: Among 685 children with CP, 169 (25%) had a congenital anomaly;
125 within the central nervous system. Spastic bilateral CP was more prevalent in
children with anomalies (42%) than in children without (34%; p=0.011). Children
with anomalies less frequently had low Apgar scores (p<0.001), but more often had
severe limitations in gross- and fine-motor function, speech impairments,
epilepsy, severe vision, and hearing impairments than children without anomalies
(p<0.03). INTERPRETATION: Although children with CP and anomalies had low Apgar
scores less frequently, they had more severe limitations in motor function and
more associated problems than children with CP without anomalies. WHAT THIS PAPER
ADDS: One in four children with cerebral palsy (CP) born at term or late preterm
has a congenital anomaly. The added value of neuroimaging to detect central
nervous system anomalies in children with CP. Children with anomalies have more
severe motor impairments. More severe clinical manifestations are not explained
by perinatal complications as indicated by low Apgar scores.
CI - (c) 2017 Mac Keith Press.

Langue : ANGLAIS