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Principles of plasticity in the developing brain

KOLB B; HARKER A; GIBB R
DEV MED CHILD NEUROL , 2017, vol. 59, n° 12, p. 1218-1223
Doc n°: 186127
Localisation : Documentation IRR

D.O.I. : http://dx.doi.org/DOI:10.1111/dmcn.13546
Descripteurs : AF11 - NORMAL

The developing brain is especially sensitive to a wide range of experiences,
showing a remarkable capacity for plastic changes that influence behavioural
outcomes throughout the lifetime. We review the principles that regulate this
plasticity in development and consider the factors that modulate the developing
brain. These include early sensory, motor, and language experience, early stress,
caregiver interactions, peer interactions, psychoactive drugs, diet, microbiome,
and the immune system. Emphasis is given to changes in behaviour, epigenetics,
and neuronal morphology. WHAT THIS PAPER ADDS: A discussion of the surprising
range of factors influencing brain development Life experiences interact
resulting in a phenomenon called metaplasticity.
CI - (c) 2017 Mac Keith Press.

Langue : ANGLAIS

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