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The Natural History of Idiopathic Scoliosis During Growth

DI FELICE F; ZAINA F; DONZELLI S; NEGRINI S
AM J PHYS MED REHABIL , 2018, vol. 97, n° 5, p. 346-356
Doc n°: 186994
Localisation : Documentation IRR

D.O.I. : http://dx.doi.org/DOI:10.1097/PHM.0000000000000861
Descripteurs : CB222 - SCOLIOSE IDIOPATHIQUE

The aim of the study was to provide a meta-analysis of current
literature concerning the natural history of idiopathic scoliosis during growth.
DESIGN: A comprehensive search of Medline, Embase, And Scopus databases was
conducted up to November 2016. Eligible works were prospective or retrospective
studies that enrolled patients with infantile idiopathic scoliosis, juvenile
idiopathic scoliosis, or adolescent idiopathic scoliosis, followed up without any
treatment from the time of detection. A meta-analysis for proportion was
performed. The following studies were grouped per diagnosis: infantile idiopathic
scoliosis, juvenile idiopathic scoliosis, and adolescent idiopathic scoliosis.
RESULTS: Of the 1797 citations screened, we assessed 61 full-text articles and
included 13 of these (2301 participants). Three studies included infantile
idiopathic scoliosis patients (347 participants), five studies included a mixed
population of juvenile idiopathic scoliosis and adolescent idiopathic scoliosis
(1330 participants), and five studies included adolescent idiopathic scoliosis
patients only (624 participants). The random pooled estimated progression rate
was 49% (95% confidence interval = 1%-97%) for infantile idiopathic scoliosis,
49% in a mixed group of patients affected by juvenile idiopathic scoliosis or
adolescent idiopathic scoliosis (95% confidence interval = 19%-79%), and 42% in
adolescent idiopathic scoliosis (95% confidence interval = 11%-73%). CONCLUSIONS:
During growth, idiopathic scoliosis tends to progress in a high percentage of
cases. The progression rate varies according to the age at diagnosis, with
infantile scoliosis being the most unpredictable. There are many confounders,
such as age, Risser sign and baseline Cobb angles that were not consistent among
studies, making the data very heterogeneous.

Langue : ANGLAIS

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