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Personalised treatment for cognitive dysfunction in individuals with schizophrenia spectrum disorders

Cognitive deficits are a well-recognised issue for individuals diagnosed with
schizophrenia spectrum disorders. Despite positive group findings for the use of
cognitive remediation (CR) interventions, there are substantial individual
differences in response to treatment. In addition, the aggregate CR literature
reports low moderate effect sizes for cognitive and functional outcomes. Based on
personalised medicine theory, this paper uses extant CR literature to examine the
individual characteristics determined to predict treatment response. These
characteristics, which fall into the broad categories of cognitive,
psychological, and biological can be used as tailoring variables to personalise
CR to an individual's unique profile. Personalisation through the use of these
tailoring variables has the potential to improve the delivery of CR to maximise
treatment outcomes.

Langue : ANGLAIS

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