Article

Increase in visceral adipose tissue (VAT) is an independent risk for
mortality and other health-related comorbidities. OBJECTIVE: To examine the
gender differences in VAT and subcutaneous adipose tissue (SAT) cross-sectional
areas (CSA) between men and women with chronic spinal cord injury (SCI). The
differences in the distribution of central adiposity were used to determine the
association of VAT and SAT to metabolic dysfunction after SCI. DESIGN: Cross-sectional design. SETTING: Hospital-based study. PARTICIPANTS: Sixteen
individuals (8 men and 8 women) with motor complete SCI were matched based on
age, time since injury, and level of injury. METHODS: Anthropometrics, dual x-ray
absorptiometry (DXA), and magnetic resonance imaging were captured to measure
lean mass, fat mass (FM), percentage FM, VAT, and SAT CSAs. Basal metabolic rate
was measured, and intravenous glucose tolerance test and lipid panel were
performed. MAIN OUTCOME MEASUREMENTS: VAT, SAT, and metabolic profile. RESULTS:
SAT CSA was 1.6 -1.75 times greater in the upper and lower trunks in women
compared to men with SCI (P < .05). VAT CSA was 1.8-2.6 times greater in the
upper and lower trunks in men compared to women with SCI (P < .05). VAT adjusted
to body weight was greater in men compared to women with SCI. High-density
lipoprotein cholesterol (HDL-C) was positively related to SAT and negatively
related to VAT. Glucose effectiveness was negatively related to lower trunk SAT
(r = -0.60, P = .02). HDL-C ratio and triglycerides were positively related to
upper VAT, lower VAT, and VAT:SAT ratio. CONCLUSION: Magnetic resonance imaging
demonstrated that there is a gender dimorphism in central adiposity in persons
with chronic SCI. This gender dimorphism in central adipose tissue distribution
may explain the higher prevalence of metabolic dysfunction in men with SCI,
especially, the decrease in the HDL-C profile. LEVEL OF EVIDENCE: IV.
CI - Copyright (c) 2018 American Academy of Physical Medicine and Rehabilitation.
Published by Elsevier Inc. All rights reserved.

Langue : ANGLAIS