Article

OBJECTIVE: To study the effect of therapeutic exercise on knee osteoarthritis
after injection of botulinum toxin type A, hyaluronate or saline. METHODS: Sixty
participants with knee osteoarthritis were randomly assigned to 3 groups:
injection of saline (control) (group A), botulinum toxin type A (group B), or
hyaluronate (group C). All participants received therapeutic exercise. Western
Ontario and McMaster Universities Osteoarthritis Index questionnaire score,
visual analogue scale pain scale, and Medical Outcomes Study
36-item Health
Survey were conducted at baseline, and at the end of the 4th and 8th weeks.
RESULTS: At end of the 4th and 8th weeks, the scores on the Western Ontario and
McMaster Universities Osteoarthritis Index questionnaire and visual analogue
scale were higher in the control group. There were significant differences in
Physical Component Summary-36 and Mental Component Summary-36 scores between the
3 groups (p <0.05) at the end of the 4th and 8th weeks, but not between groups A
(control) and C (hyaluronate) at the end of the 4th week. No changes were seen on
magnetic resonance imaging and X-ray images of the affected knees after the
intervention. CONCLUSION: Therapeutic exercise plus botulinum toxin type A or
hyaluronate injection can significantly reduce pain and improve knee functioning.
Botulinum toxin type A plus therapeutic exercise appears to be more effective.

Langue : ANGLAIS