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Efficacy of Injected Corticosteroid Type, Dose, and Volume for Pain in Large Joints

Corticosteroid injections are commonly used in the treatment of disorders of the
large joints. This review assimilates the available literature on corticosteroid
injections into the glenohumeral joint, subacromial space, hip joint, and knee
joint. A systematic method to review available literature revealed 84 articles
that fit the inclusion criteria.
For each injection location, four items were
examined: overall efficacy of injection, superior type of steroid, superior dose
of steroid, and superior volume of injectate. Most research demonstrates positive
short-term outcomes in pain and function for corticosteroid injections of the
large joints. Methylprednisolone and triamcinolone seem similar in efficacy, with
minor differences seen in specific studies. Larger doses may last longer, but
need to be balanced with the systemic effects from higher doses. Volume has not
been studied extensively.
Due to heterogeneity in study types, subject
populations, and outcomes, it is not possible to identify a single defining trend
for a superior type, dose, or volume of steroid. Future prospective studies
examining these factors may better reveal the optimum regimen for each injection
location.
LEVEL OF EVIDENCE: III.
CI - Copyright (c) 2018 American Academy of Physical Medicine and Rehabilitation.
Published by Elsevier Inc. All rights reserved.

Langue : ANGLAIS

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