Article

This cross-sectional study aims to determine whether leg strength asymmetries are
associated with walking ability, objective measures of fatigability, or
subjective perceptions of fatigue. Maximal knee extensor strength was assessed in
19 patients with multiple sclerosis (PwMS), and a symmetry index was calculated.
Walking ability was determined through the total distance covered during a 6-min
walk test (6MWT) and fatigability by calculating the change in distance covered
between minutes 6 and 1. Perceptions of fatigue were assessed using the Fatigue
Severity Scale and by obtaining ratings of perceived exertion during the first
and final minute of the 6MWT. PwMS covered less distance (P=0.01) and perceived
greater exertion (P<0.01) during minute 6 compared with minute 1. Knee extensor
strength was asymmetric (P<0.01). The magnitude of asymmetry did not correlate
with walking ability, fatigability, or measures of fatigue. Knee extensor
strength asymmetry may not play an important role in prolonged walking
performance in PwMS.

Langue : ANGLAIS