Article

OBJECTIVES: To compare plasma concentrations of oxidized low-density lipoprotein
(oxLDL) and adrenaline during exercise between persons with spinal cord injury
(SCI) and able-bodied (AB) individuals. DESIGN: Randomized controlled study.
SETTING: Human laboratory at a medical university. PARTICIPANTS: Persons with SCI
(n=7) and AB individuals (n=9). INTERVENTION: Two-hour arm crank ergometer
exercise at 60% maximum oxygen consumption. MAIN OUTCOME MEASURES:
Plasma oxLDL
and adrenaline levels. RESULTS: Exercise significantly increased plasma
adrenaline levels in AB persons (mean +/- SD: rest, 45.4+/-32.2 pg/mL; exercise,
200.9+/-113.7 pg/mL; P<.05) and persons with SCI; however; the magnitude of the
increase in those with SCI was attenuated (mean +/- SD: rest, 45.4+/-14.0 pg/mL;
exercise, 83.0+/-55.8 pg/mL; P<.05). Exercise also significantly increased plasma
oxLDL levels in AB persons (mean +/- SD: rest, 102.2+/-30.2 U/L; exercise,
179.7+/-60.0 U/L; P<.05), but not in persons with SCI (mean +/- SD: rest,
124.3+/-66.0 U/L; exercise, 138.9+/-59.5 U/L). CONCLUSIONS: The results suggest
that increases in plasma adrenaline levels during exercise contribute to the
increase in plasma oxLDL levels.
CI - Copyright (c) 2012 American Congress of Rehabilitation Medicine. Published by
Elsevier Inc. All rights reserved.

Langue : ANGLAIS