Article

OBJECTIVE: To examine the independent association between various anthropometric
indicators and standard clinical markers of cardiometabolic health risk among
adults with cerebral palsy (CP). DESIGN: Cross-sectional study. SETTING: Clinical
center for CP treatment and rehabilitation. PARTICIPANTS: Adults with CP (N=43)
with a mean age +/- SD of 37.3+/-13.2 years, and Gross Motor Function
Classification System (GMFCS) levels of I-V. INTERVENTIONS: Not applicable. MAIN
OUTCOME MEASURES: Adults with CP were assessed for body mass index (BMI), waist
circumference (WC), hip circumference (HC), waist-to-hip ratio (WHR),
waist-to-height ratio (WtHR), and serum lipid profiles. Data were analyzed with
multiple regression analysis and general linear models, and are reported as means
+/- SDs. RESULTS: Mean BMI was 29.1+/-7.8kg/m(2). BMI was not associated with any
measures of cardiometabolic risk. Using GMFCS categories (2 groups: GMFCS levels
I-III and IV-V), BMI was significantly lower among GMFCS levels IV-V
(24.2+/-6.2kg/m(2)) versus GMFCS levels I-III (30.1+/-7.6kg/m(2)). WC and WtHR
were not correlated with any cardiometabolic outcomes. Conversely, measures of
WHR were independently associated with various indices of risk, including total
cholesterol to high-density lipoprotein (HDL) cholesterol ratio (r=.45; P<.05),
HDL cholesterol (r=-.51; P<.01), and triglycerides (r=.40; P<.05), suggesting
that greater WHR was indicative of elevated risk. CONCLUSIONS: It is likely that
WHR represents a stronger predictor of risk, because this measure was robustly
and independently associated with 3 primary clinical markers of cardiometabolic
health in adults with CP.
CI - Copyright (c) 2012 American Congress of Rehabilitation Medicine. Published by
Elsevier Inc. All rights reserved.

Langue : ANGLAIS