Article

OBJECTIVE: To investigate the efficacy and feasibility of home-based inspiratory
muscle training in patients with bronchiectasis. A prospective,
single-blind, randomized, controlled study. SETTING: Outpatient clinic of a
tertiary care medical centre. METHODS: Twenty-six patients with bronchiectasis
were randomly divided into inspiratory muscle training and control groups. In the
inspiratory muscle training group (n = 13), the training programme started with
an intensity of 30% maximal inspiratory pressure (MIP), which was increased by 2
cmH(2)O each week, for 30 minutes daily, 5 days a week for eight weeks. The control group (n = 13) did not receive inspiratory muscle training. Main outcome
measures included spirometry, resting oxyhaemoglobin saturation by pulse oximetry
(SpO(2)), lowest SpO(2) and Borg Scale during 6-minute walking tests, 6-minute
walking distance (6MWD), 6-minute walking work (6M(work)), MIP, maximal
expiratory pressure (MEP) and St George's Respiratory Questionnaire. RESULTS:
There were significant differences in change from baseline in 6MWD (411.9 (133.5)
vs. 473.2 (117.2) m, P = 0.021), 6M(work) (21 051.0 (8286.7) vs. 23 915.5
(8343.0) kg-m, P = 0.022), MIP (60.8 (21.8) vs. 84.6 (29.0) cmH(2)O, P = 0.004),
and MEP (72.3 (31.1) vs. 104.2 (35.7) cmH(2)O, P = 0.004) in the inspiratory
muscle training group. Significant improvements in both MIP (23.8 (25.3) vs. 2.3
(16.4) cmH(2)O, adjusted P-value = 0.005) and MEP (31.9 (30.8) vs. 11.5 (20.8)
cmH(2)O, adjusted P-value = 0.038) levels after adjusting for age by linear
regression analysis were observed between groups. CONCLUSIONS: An eight-week
home-based inspiratory muscle training is feasible and effective in improving
both inspiratory and expiratory muscle strength, but has no effect on respiratory
function and quality of life in patients with bronchiectasis.

Langue : ANGLAIS