Article

The cognitive and psychiatric aspects of adult movement disorders are well
established, but specific behavioural profiles for paediatric movement disorders
have not been delineated. Knowledge of non-motor phenotypes may guide treatment
and determine which symptoms are suggestive of a specific movement disorder and
which indicate medication effects. METHOD: The goal of this review is to outline
the known cognitive and psychiatric symptoms associated with paediatric movement
disorders. We used a systematic approach, via PubMed, and reviewed over 400
abstracts of studies of selected disorders, of which 88 papers reporting
paediatric non-motor symptoms are summarized. RESULTS: Obsessive-compulsive
disorder was manifest in children with paediatric autoimmune neuropsychiatric
disorders associated with streptococcal infections and Sydenham chorea. Children
with opsoclonus-myoclonus syndrome had, for the most part, cognitive and
behavioural problems, and attention-deficit-hyperactivity disorder was reported
as a major comorbidity in Tourette syndrome, stereotypies, and restless legs
syndrome. Symptoms of depression and anxiety were more frequent in individuals
with idiopathic dystonia. Affective disorders were suggestive of Wilson disease.
Cognitive decline was common in children with juvenile Huntington disease. A limitation of this review was the lack of systematic assessment in paediatric
movement disorders for evaluation and uniform definitions. INTERPRETATION:
Although the literature in non-motor phenomena is still emerging, recognition of
salient cognitive and psychiatric phenomena may facilitate management of
paediatric movement disorders.
CI - (c) The Authors. Developmental Medicine & Child Neurology (c) 2011 Mac Keith
Press.

Langue : ANGLAIS