Article

Active stretch is necessary for regulating muscle fiber length (ie, the number of
series sarcomeres). Elevated cytoplasmic calcium is the proposed component of
contractile activity required to activate signaling pathways for sarcomere number
regulation. Passive stretch reduces muscle tissue stiffness, most likely by
signaling connective tissue remodeling via fibroblasts. Passive stretch may
induce sarcomere addition if the muscle fibers are lengthened sufficiently to
raise cytoplasmic calcium through stretch-activated calcium channels. The
magnitude of stretch in vivo is limited by the physiologic range of movement and
stretch pain tolerance. The greatest effect of stretching muscle fibers is
expected when the lengthening exceeds the optimum fiber length (Lo).
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Langue : ANGLAIS