Article

The aim of this trial was to compare the efficacy of triamcinolone
acetonide and procaine HCl with that of placebo in the treatment of carpal tunnel
syndrome. Design: This prospective, randomized placebo-controlled trial included
57 patients (90 median nerves). Ninety median nerves were randomly assigned to 1
of 3 groups: group 1 was injected with 1 ml 0.09% saline, group 2 was injected
with 40 mg triamcinolone acetonide, and group 3 was injected with 4 ml 1%
procaine HCl. Clinical and electrophysiological evaluations were performed at
study onset, and at 2 and 6 months post-treatment. Results: At study onset no
significant differences were observed between groups with respect to clinical and
electrophysiological parameters. Clinical and electrophysiological evaluations
was improved significantly in groups 2 and 3 at post-treatment (p < 0.05). No
significant changes were observed in group 1 (p > 0.05). Moreover, groups 2 and 3
had better scores than group 1 at 2 and 6 months post-treatment(p < 0.05). There
was no difference between groups 2 and 3 in terms of change scores of any terms
at post-treatment (p > 0.05). Conclusion: Triamcinolone acetonide and procaine
HCl injections are effective regarding short- and long-term outcomes compared
with placebo injections, and procaine HCl injection was as effective as steroid
injection.

Langue : ANGLAIS