Article

Estimate changes in prevalence of Major Depressive Disorder (MDD) 1
to 5 years post spinal cord injury (SCI); Identify demographic, injury, and
discharge factors associated with MDD at 1 and 5 years post-injury; Identify
modifiers of changes in MDD. Design: Retrospective. Setting: Model Spinal Cord
Injury System. Participants: 2,256 adult participants enrolled in the National
Spinal Cord Injury Statistical Center between 1999 and 2004. Main Outcome
Measure: MDD as determined by the Patient Health Questionnaire-9 (PHQ-9).
Results: Prevalence of MDD was 11.9% at 1 year and 9.7% at 5 years post SCI. Odds
of MDD decreased significantly 1 to 5 years post-injury (odds ratio=1.26, 95%
confidence interval=1.02, 1.56). At 1 year post-injury, the odds of MDD was
greater for persons 35-55 years old at injury, unemployed, having an indwelling
catheter or voiding bladder management at discharge, and higher scores on ASIA
motor index. At 5 years post-injury, the odds of MDD were greater for females,
persons 35-55 years old at injury, those with a high school education or less,
those having an indwelling catheter, voiding, and no bladder management at
discharge, and higher scores on ASIA motor index. Sex was the only significant
modifier.Conclusions: MDD occurs commonly 1 to 5 years post SCI.
Sociodemographic, injury, and discharge factors are associated with the
development and changes in depression. Future research should expand upon current
findings in order to identify, prevent, and reduce the prevalence of MDD after
SCI.

Langue : ANGLAIS