Article

Discussion persists as to whether obesity negatively
influences the outcome of hip arthroplasty. We performed a meta-analysis with the
primary research question of whether obesity has a negative effect on short- and
long-term outcome of total hip arthroplasty. METHODS:
We searched the literature
and included studies comparing the outcome of hip arthroplasty in different weight groups. The methodology of the studies included was scored according to
the Cochrane guidelines. We extracted and pooled the data. For continuous data,
we calculated a weighted mean difference and for dichotomous variables we
calculated a weighted odds ratio (OR). Heterogeneity was calculated using I(2)
statistics. RESULTS: 15 studies were eligible for data extraction. In obese
patients, dislocation of the hip (OR = 0.54, 95% CI: 0.38-0.75) (10 studies, n =
8,634), aseptic loosening (OR = 0.64, CI: 0.43-0.96) (6 studies, n = 5,137),
infection (OR = 0.3, CI: 0.19-0.49) (10 studies, n = 7,500), and venous
thromboembolism (OR = 0.56, CI: 0.32-0.98) (7 studies, n = 3,716) occurred more
often. Concerning septic loosening and intraoperative fractures, no statistically
significant differences were found, possibly due to low power. Subjective outcome
measurements did not allow pooling because of high heterogeneity (I(2) = 68%).
INTERPRETATION: Obesity appears to have a negative influence on the outcome of
total hip replacement.

Langue : ANGLAIS