Article

The aim of this study was to investigate the additive effect of the
active form of vitamin D3 on the gain in back extensor strength through a back
extensor exercise. DESIGN: A total of 107 postmenopausal women with osteoporosis
were randomly divided into two groups: the D3 group and the control group. Both
groups were treated with calcium and alendronate and undertook the back extensor
exercise. Alfacalcidol was prescribed only to the D3 group. RESULTS: There was no
significant difference in the demographic data between the two groups.
Ninety-four participants who completed a 4-mo intervention were subjected to
per-protocol analysis. There was no significant difference in the improvement in
back extensor strength between two the groups (P = 0.349). All subjects were
further categorized into two subgroups by age. In the older subgroup (>/=68 yrs),
no significant difference was found in the improvement in back extensor strength
(P = 0.316). In the younger subgroup (<68 yrs), the back extensor strength in the
D3 group was significantly more improved than in the control group (P = 0.034).
CONCLUSIONS: The results of this study suggest that the administration of the
active form of vitamin D3 enhances the beneficial effects of the back extensor
exercise in patients younger than those in their late 60s.

Langue : ANGLAIS