Article

The aim of the study was to determine the relationships between
functional outcomes, clinical symptoms, and health-related quality of life among
patients with malignant brain tumors receiving interdisciplinary outpatient
rehabilitation. DESIGN: A prospective study of 49 adults with malignant brain
tumors participating in outpatient therapies was performed. Outcome measures
included the Functional Assessment of Cancer Therapy-Brain (FACT-Br) for
health-related quality of life and the Patient-Reported Outcome Measures
Instrument Survey (PROMIS) Depression and Pain Behavior scales measured at
admission, discharge, 1 and 3 mos after discharge. Day Rehabilitation Outcome
Scale (DayROS), a functional measure, was measured at admission and discharge.
RESULTS: The FACT-Br scores, PROMIS pain, and PROMIS depression scores did not
significantly change. There were many negative associations seen between FACT-Br
and PROMIS depression (all P < .0001) and less associations with PROMIS pain.
There was a positive correlation between Day Rehabilitation Outcome Scale and
FACT-Br (P = .0058) and a negative association with PROMIS pain (P = .028), but
not with PROMIS depression. There were no correlations between Day Rehabilitation
Outcome Scale gains and change in PROMIS depression, FACT-Br total, or PROMIS
pain. CONCLUSIONS: Health-related quality of life, pain, and depression did not
worsen. Patients who reported less depression and pain had better reported
health-related quality of life. Level of function was also associated with HRQOL
and pain, but not depression.

Langue : ANGLAIS