Article

Bone sarcomas are the fourth most common cancer in individuals under 25 years.
Limb salvage procedures have become increasingly popular for the treatment of
osteosarcomas as they have functional and psychological benefits over traditional
amputative procedures. The purpose of this paper was to evaluate kinematic and
kinetic characteristics of patient's post-limb salvage and examine key predictive
factors of gait dysfunction. A retrospective outcome study was undertaken on 20
limb salvage patients (10 females, 10 males) recruited from the Queensland Bone
Tumour Registry. Kinematic and kinetic data were collected using a 3D motional
analysis system and three force platforms. Loading response knee flexion in the
affected lower limb was reduced compared to the unaffected lower limb (P<0.001)
and the control group (P<0.001), although, closer examination of results showed
two contrasting patterns of knee flexion during loading. Multiple regression
analysis showed that muscular integrity (i.e. strength, ROM and residual mass)
was the most predictive factor of function following limb salvage surgery. ANOVA
showed that patients treated with the Stanmore SIMLES prostheses exhibited
superior torque and power production at the ankle during late stance compared to
those treated with the Stryker HMRS. In summary, the results showed that limb
salvage patients adopted a gait pattern that reduced the moment demand at the
knee and hip, suggesting a compensation for pain, reduced stability and/or muscle
weakness.

Langue : ANGLAIS