Article

OBJECTIVE: To study physical behavior in detail in fatigued persons with multiple
sclerosis (MS). DESIGN: Case-control explorative study.
SETTING: Outpatient
rehabilitation department and participants' daily environment. PARTICIPANTS:
Fatigued persons with MS (n=23) were selected from a randomized controlled trial.
Cases were matched by age and sex to healthy, nonfatigued controls (n=23).
Eligible persons with MS were severely fatigued (Checklist Individual Strength
fatigue domain mean score, 43.2+/-6.6) and ambulatory (Expanded Disability Status
Scale mean score, 2.5+/-1.5). INTERVENTIONS: Not applicable. MAIN OUTCOME
MEASURES: Measurements were performed using an accelerometer over 7 days.
Outcomes included the following: amount of physical activity expressed in counts
per day, counts per minute (CPM), and counts per day period (morning, afternoon,
evening); duration of activity intensity categories (sedentary, light physical
activity, moderate-to-vigorous physical activity [MVPA]); and distribution of
MVPA and sedentary periods over the day. RESULTS: Persons with MS had fewer
counts per day (mean difference, -156x10(3); 95% confidence interval [CI],
-273x10(3) to -39x10(3); P=.010), had fewer CPM (mean difference, -135; 95% CI,
-256 to -14; P=.030), and were less physically active in the morning (mean
difference, -200; 95% CI, -389 to -11; P=.039) and evening (mean difference,
-175; 95% CI, -336 to -14; P=.034) than controls. Persons with MS spent a higher
percentage of their time sedentary (mean difference, 5.6; 95% CI, .1-11.1;
P=.045) and spent less time at the higher MVPA intensity (mean difference, -2.4;
95% CI, -4.7 to -0.09; P=.042). They had fewer MVPA periods (mean difference, 29;
95% CI, -56.2 to -2.6; P=.032) and a different distribution of sedentary (mean
difference, .033; 95% CI, .002 to .064; P=.039) and MVPA periods (mean
difference, -.08; 95% CI, -.15 to -.01; P=.023). CONCLUSIONS: Detailed analyses
of physical behavior showed that ambulatory fatigued persons with MS do differ
from healthy controls not only in physical activity level, but also in other
physical behavior dimensions (eg, day patterns, intensity, distribution).
CI - Copyright (c) 2015 American Congress of Rehabilitation Medicine. Published by
Elsevier Inc. All rights reserved.

Langue : ANGLAIS